What you should know before surgery.

When you're scheduled for abdominal or pelvic surgery, the procedure becomes your main focus. But, it's important to think about what happens after surgery, too. Adhesions, or internal scar tissue, are a common problem after open surgery on the pelvis or abdomen. Adhesions can lead to serious problems including chronic pelvic pain, bowel obstruction, and issues with future operations.1-3 There are steps your doctor can take, such as using Seprafilm®, to help prevent adhesions. Seprafilm is the most widely used adhesion barrier.4

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I'm having a C-Section

More than half of women get adhesions after their first C-Section.5

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I'm having gynecologic surgery

Gynecologic surgery can lead to adhesions. In one study, 93% of patients formed adhesions after pelvic or abdominal surgery.6

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I'm having colorectal or abdominal surgery

Surgery on the bowels or abdomen can lead to adhesions. In one study, 93% of patients formed adhesions after abdominal or pelvic surgery. 6

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Indication
Seprafilm® Adhesion Barrier is indicated for the reduction of post-surgical adhesions in patients undergoing abdominal or pelvic laparotomy.

Important Safety Information
Seprafilm should not be wrapped around an intestinal anastomosis as such usage may result in increased anastomotic leak related events, such as abscess or peritonitis. The safety and effectiveness of Seprafilm has not been established in combination with other adhesion prevention products and/or in surgical procedures not within the abdominopelvic cavity. The safety and effectiveness of Seprafilm has also not been evaluated in cases of pregnancy, malignancy, or frank infection. The type and frequency of adverse events reported are consistent with events typically seen following abdominopelvic surgery when used as directed.

Please see full prescribing information.

References

  1. Keltz MD, Gera PS, Olive DL. Prospective randomized trial of right-sided paracolic adhesiolysis for chronic pelvic pain. J Soc Laparoendosc Surg. 2006;10(4):443-446.
  2. Ellis H, Moran BJ, Thompson JN, et al. Adhesion-related hospital readmissions after abdominal and pelvic surgery: a retrospective cohort study. Lancet. 1999;353(9163):1476-1480.
  3. van der Krabben AA, Dijkstra FR, Nieuwenhuijzen M, Reijnen MMPJ, Schaapveld M, van Goor H. Morbidity and mortality of inadvertent enterotomy during adhesiotomy. Br J Surg. 2000;87(4):467-471.
  4. Data on file, Genzyme Corp.
  5. Lyell DJ, Caughey AB, Hu E, Daniels K. Peritoneal closure at primary Cesarean delivery and adhesions. Obstet Gynecol. 2005;106(2):275-280
  6. Menzies D, Ellis H. Intestinal obstruction from adhesions—how big is the problem? Ann R Coll Surg Engl. 1990;72(1):60-63.