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Adhesions and Infertility

When adhesions form between the ovaries, fallopian tubes, uterus, or pelvic walls, they can block the passage of the egg from the ovary into or through the fallopian tubes, causing infertility.1 In fact, adhesions can account for up to 40% of infertility cases.1 Adhesions may also increase the risk of ectopic pregnancy.2 Often, patients undergo surgery to remove the adhesions that may be causing their infertility.

Infertility can be emotionally trying for couples and their families. Find online resources and support for infertility.
Fallopian Tube
Either of the pair of tubes that carry the eggs from the ovary to the uterus—also called the uterine tubes
Full glossary
Infertility
The inability to become pregnant.
Full glossary
Adhesions
Internal scars that may form after surgery on or between internal organs and/or body tissue. Adhesions between tissues can twist and pull organs out of their normal places.
Full glossary
Uterus
A female reproductive organ for containing and providing nourishment to a fetus during development prior to birth (often referred to as the womb).
Full glossary
Ovaries
Female reproductive organs that produce eggs and female sex hormones.
Full glossary
Ectopic Pregnancy
A pregnancy in which the fertilized egg implants outside of the uterus, usually in the fallopian tube.
Full glossary
1. DiZerega GS.  Peritoneal repair and postsurgical adhesion formation. In: Management of Common Problems in Obstetrics & Gynecology. Mishell DR, Goodwin Murphy T, Brenner PF, eds. Malden, MA: Blackwell Publishing; 2002: 267-271.
 
1. DiZerega GS.  Peritoneal repair and postsurgical adhesion formation. In: Management of Common Problems in Obstetrics & Gynecology. Mishell DR, Goodwin Murphy T, Brenner PF, eds. Malden, MA: Blackwell Publishing; 2002: 267-271.
 
2. Michalas S, Minaretzis D, Tsionou C, Maos G, Kioses E, Aravantinos D. Pelvic surgery, reproductive factors and risk of ectopic pregnancy: a case controlled study. Int J Gynaecol Obstet. 1992;38(2):101-105.
 

 
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Indication

Seprafilm® Adhesion Barrier is used to reduce internal scarring (adhesions) after open abdominal/pelvic surgery.

Important Safety Information

Seprafilm should not be wrapped around a reconnected bowel as this may lead to increased side effects, such as abdominal infections. The safety and effectiveness of Seprafilm has not been established in combination with other adhesion prevention products and/or in surgeries outside of the abdomen or pelvis. The safety and effectiveness of Seprafilm has also not been evaluated in cases of pregnancy, cancer, or known infection. Side effects are consistent with those typically seen following abdominal/pelvic surgery when used as directed.

Please see the Seprafilm Package Insert for full product information and talk to your doctor.

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