In one particular study, patients that received Seprafilm were 8.5 times more likely to be adhesion free.2

Seprafilm helps prevent adhesions, or internal scars, after open surgery on the abdomen or pelvis. It's a clear, thin film that's applied during surgery. It separates organs and body tissues from one another to help prevent them from sticking together and forming adhesions as they heal. Seprafilm stays in place for 7 days—the time during which adhesions would form—and then is absorbed and eliminated naturally by your body.3

How does Seprafilm work?

From application to absorption, get the basics on Seprafilm and how it can help you. 

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Indication
Seprafilm® Adhesion Barrier is indicated for the reduction of post-surgical adhesions in patients undergoing abdominal or pelvic laparotomy.

Important Safety Information
Seprafilm should not be wrapped around an intestinal anastomosis as such usage may result in increased anastomotic leak related events, such as abscess or peritonitis. The safety and effectiveness of Seprafilm has not been established in combination with other adhesion prevention products and/or in surgical procedures not within the abdominopelvic cavity. The safety and effectiveness of Seprafilm has also not been evaluated in cases of pregnancy, malignancy, or frank infection. The type and frequency of adverse events reported are consistent with events typically seen following abdominopelvic surgery when used as directed.

Please see full prescribing information.

References

  1. Data on file, Genzyme Corp.
  2. Becker JM, Dayton MT, Fazio VW, et al. Prevention of postoperative abdominal adhesions by a sodium hyaluronate-based bioresorbable membrane: a prospective, randomized, double-blind multicenter study. J Am Coll Surg. 1996;183(4):297-306.
  3. Seprafilm Adhesion Barrier [package insert]. Cambridge, MA: Genzyme Biosurgery; 2008.