Seprafilm® has been shown to reduce adhesions in a range of surgical procedures, including radical pelvic surgery2
In recent studies Seprafilm was shown to reduce adhesions observed at subsequent surgeries, resulting in
- Fewer inadvertent injuries3
- Less operative time4
- Reduced blood loss4
Seprafilm is a temporary, bioresorbable adhesion barrier proven to reduce the incidence, extent, and severity of adhesions in patients undergoing abdominal or pelvic laparotomy.5,6 Seprafilm is proven safe and effective even in cases without complete hemostasis; however, we do recommend the field should be as dry as possible.1,3,4, which reduces postoperative adhesions and related complications.6,7
To order Seprafilm for your operating room, or to request a product demonstration, call 1-800-261-1570 and select option 1, or fill out an order form.
Adhesions are a common consequence of pelvic surgery
Adhesions may form after up to 95% of gynecologic laparotomies.1
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Accommodate a wide range of surgeries with Seprafilm
Seprafilm has multiple configurations; find out which configuration is right for your practice.
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Seprafilm® Adhesion Barrier is indicated for the reduction of post-surgical adhesions in patients undergoing abdominal or pelvic laparotomy.
Important Safety Information
Seprafilm should not be wrapped around an intestinal anastomosis as such usage may result in increased anastomotic leak related events, such as abscess or peritonitis. The safety and effectiveness of Seprafilm has not been established in combination with other adhesion prevention products and/or in surgical procedures not within the abdominopelvic cavity. The safety and effectiveness of Seprafilm has also not been evaluated in cases of pregnancy, malignancy, or frank infection. The type and frequency of adverse events reported are consistent with events typically seen following abdominopelvic surgery when used as directed.
Please see full prescribing information.
Menzies D, Ellis H. Intestinal obstruction from adhesions—how big is the problem? Ann R Coll Surg Engl. 1990;72(1):60-63.
Bristow RE, Montz FJ. Prevention of adhesion formation after radical oophorectomy using a sodium hyaluronate-carboxymethylcellulose (HA-CMC) barrier. Gynecol Oncol. 2005;99(2):301-308.
Tang C-L, Seow-Choen F, Fook-Chong S, Eu K-W. Bioresorbable adhesion barrier facilitates early closure of the defunctioning ileostomy after rectal excision: a prospective randomized trial. Dis Colon Rectum. 2003;46(9):1200-1207.
Fushiki H, Ikoma T, Kobayashi H, Yoshimoto H. Efficacy of Seprafilm as an adhesion prevention barrier in cesarean sections. Obstet Gynecol Treatment. 2005;91(5):557-561.
Diamond MP. Reduction of adhesions after uterine myomectomy by Seprafilm membrane (HAL-F): a blinded, prospective, randomized, multicenter clinical study. Fertil: Steril 1996;66(6);904-910.
Becker JM, Dayton MT, Fazio VW, et al. Prevention of postoperative abdominal adhesions by a sodium hyaluronate-based bioresorbable membrane: a prospective, randomized, double-blind multicenter study. J Am Coll Surg. 1996;183(4):297-306.
Seprafilm Adhesion Barrier [package insert]. Cambridge, MA: Genzyme Biosurgery; 2008.