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Clinical BenefitsSEPRAFILM® is proven to reduce post-operative adhesions and related complications. It has been studied in more than 4,000 patients and in 20 published clinical reports.1 
Reduction in Reoperative Adhesive Small Bowel ObstructionIn a prospective, randomized, controlled, blinded, multicenter study of patients receiving SEPRAFILM during intestinal resection, SEPRAFILM reduced reoperation required for adhesive SBO by 47% relative to untreated controls.2 Reduction in Reoperative ComplexityIn a series of prospective clinical studies in which SEPRAFILM was placed at the initial procedure, SEPRAFILM reduced adhesions observed at subsequent surgery, resulting in:
Reduction in Adhesions and Complexity at Repeat C-SectionIn a study of patients receiving SEPRAFILM at primary C-section, SEPRAFILM significantly reduced adhesions, resulting in decreased procedure and delivery times at repeat C-section.4  
1. Data on File, Genzyme Corporation
2. Fazio VW, Cohen Z, Fleshman JW, et al. Reduction in adhesive small-bowel obstruction by Seprafilm Adhesion Barrier after intestinal resection. Dis Colon Rectum. 2005;49:1-11.
3. Tang C-L, Seow-Choen F, Fook-Chong S, Eu K-W. Bioresorbable adhesion barrier facilitates early closure of the defunctioning ileostomy after rectal excision. Dis Colon Rectum. 2003;46:1200-1207.
3. Tang C-L, Seow-Choen F, Fook-Chong S, Eu K-W. Bioresorbable adhesion barrier facilitates early closure of the defunctioning ileostomy after rectal excision. Dis Colon Rectum. 2003;46:1200-1207.
4. Fushiki H, Ikoma T, Kobayashi H, Yoshimoto H. Efficacy of SEPRAFILM as an Adhesion Barrier in Cesarean Sections. Obstetric and Gynecological Treatment [Japanese]. 2005;91(5):557-561.
4. Fushiki H, Ikoma T, Kobayashi H, Yoshimoto H. Efficacy of SEPRAFILM as an Adhesion Barrier in Cesarean Sections. Obstetric and Gynecological Treatment [Japanese]. 2005;91(5):557-561.
4. Fushiki H, Ikoma T, Kobayashi H, Yoshimoto H. Efficacy of SEPRAFILM as an Adhesion Barrier in Cesarean Sections. Obstetric and Gynecological Treatment [Japanese]. 2005;91(5):557-561.
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