The Science
SEPRAFILM Adhesion Barrier is a temporary, bioresorbable adhesion barrier proven to reduce the incidence, extent, and severity of adhesions in patients undergoing abdominal or pelvic laparotomy. It physically separates traumatized, adhesiogenic tissues and organs while normal tissue repair takes place.
Upon hydration, SEPRAFILM becomes a gel within 24 to 48 hours. This gel remains in place during the critical seven-day healing period — the time during which new adhesions typically form.1 It slowly resorbs and is excreted from the body in less than 28 days.
SEPRAFILM is composed of two chemically modified polysaccharides: hyaluronic acid and carboxymethylcellulose. Hyaluronic acid (HA) is a naturally occurring polysaccharide expressed throughout the human body. Carboxymethylcellulose (CMC), also a polysaccharide, is a derivative of cellulose. Both are common components in pharmaceuticals, foods, and cosmetics. These components’ properties render SEPRAFILM hydrophilic so it doesn’t require suturing and stays where it is applied until reabsorbed.